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Monosaccharide Autoxidation in Health and Disease

By Thornalley, Paul J.

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Book Id: WPLBN0000001349
Format Type: PDF eBook
File Size: 0.7 MB
Reproduction Date: 2005

Title: Monosaccharide Autoxidation in Health and Disease  
Author: Thornalley, Paul J.
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Thornalley, P. J. (n.d.). Monosaccharide Autoxidation in Health and Disease. Retrieved from

Government Reference Publication

Excerpt: Susceptibility of Monosaccharides to Oxidative Degradation The spontaneous reaction of monosaccharides with oxygen in aqueous solution under physiological conditions (pH 7.4, 37?C) is, perhaps, one aspect of chemistry of monosaccharides which does not normally give the toxicologist cause for concern. Yet this process has been known for many years (1) and produces potentially noxious a-oxoaldehydes, otherwise known as osones and glycosuloses. Over the short term (hours), sterile aqueous solutions of monomeric and oligomeric hexoses can be stored without significant deterioration by nonenzymic oxidative processes.


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