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Oxidant Gases

By Evans, Michael J.

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Book Id: WPLBN0000030323
Format Type: PDF eBook
File Size: 2.4 MB
Reproduction Date: 2005

Title: Oxidant Gases  
Author: Evans, Michael J.
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Evans, M. J. (n.d.). Oxidant Gases. Retrieved from

Government Reference Publication

Introduction: The airways of the lung are lined with a layer of ciliated and nonciliated cells (I). In the large airways (trachea, main bronchi, and bronchi), the nonciliated cell population comprises serous, goblet, intermediate, and basal cells. In the small airways (terminal and respiratory bronchioles), Clara cells make up the nonciliated cell population. Goblet, serous, and Clara cells usually protrude above adjacent ciliated cells and contain secretory granules. In the alveoli, large, flat squamous cells (Type I) cover about 97% of the alveolar surface (2). The remaining 3% of the gas-exchanging area is covered by cuboidal ceIls (Type IT), which usually contain secretory granules (lamellar bodies). Beneath the epithelial surface is the interstitium, which is composed of acellular supporting materials (collagen and elastin), fibroblasts, and migratory cells. Within the interstitium there is a vast network of capillaries lined with endothelial cells. Together, the Type I cell, interstitium, and endothelial cell make up the air-blood barrier of the lung. Macrophages are present in the surface-active film covering the alveoli. This alveolar lining layer is continuous with a mucoid layer lining the airways.


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