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Evaluation of Chromosome Aberration Effects of Chemicals on Mouse Germ Cells

By Generoso, W. M.

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Book Id: WPLBN0000052893
Format Type: PDF eBook
File Size: 0.6 MB
Reproduction Date: 2005

Title: Evaluation of Chromosome Aberration Effects of Chemicals on Mouse Germ Cells  
Author: Generoso, W. M.
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Generoso, W. M. (n.d.). Evaluation of Chromosome Aberration Effects of Chemicals on Mouse Germ Cells. Retrieved from

Government Reference Publication

Excerpt: Chromosomal aberrations induced by chemicals represent a class of genetic darnage that causes concern as a hazard to the human population. It is well known that many human genetic defects result from chromosomal anomalies of one type or another. However, for two main reasons it has not been easy to evaluate this chemical hazard: first, unlike carcinogenic or teratogenic effects, no agent has yet been implicated as mutagenic to the human population, and many important experiments cannot be done directly on humans; second, the amount of information on the basic nature of chemical effects on mammalian germ cells is still very small. Althoogh there has been a dramatic increase in the number of papers published on mammalian mutagenesis in the past few years, there is still much basic information we need.


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