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The Fifth Plot of the Carcinogenic Potency Database : Results of Animal Bioassays Published in the General Literature through 1988 and by the National Toxicology Program through 1989

By Gold, Lois Swirsky

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Book Id: WPLBN0000057273
Format Type: PDF eBook
File Size: 3.5 MB
Reproduction Date: 2005

Title: The Fifth Plot of the Carcinogenic Potency Database : Results of Animal Bioassays Published in the General Literature through 1988 and by the National Toxicology Program through 1989  
Author: Gold, Lois Swirsky
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)

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Gold, L. S. (n.d.). The Fifth Plot of the Carcinogenic Potency Database : Results of Animal Bioassays Published in the General Literature through 1988 and by the National Toxicology Program through 1989. Retrieved from http://www.ebooklibrary.org/


Description
Government Reference Publication

Excerpt
Excerpt: This paper is the fifth plot oftbe heminogenie htency D a h k (CPDB) thal firnappeadin this journal in 1!J84(1-5). W report hereresultsof earcimgeneris binasrays publbhed in thegeneral literature betweenJanuary l987 andDecember 1988, and in technical reporla of the National Tmricologv Pmgram between July W87 and December 1989. This supplement include resultsof 412 long-term, ehmnic experiments01 147 tesleompoundsand repor6 the same information about each experiment in the same plot format asthe earlier papers: the speciesand strain of t a t animal, the mute and duration of compound administration, dose level and other aspects of experimental pmtoeol, histopathology and tumor incidence, TDso (carcinogenic potency) and its statistical significance, d m respmse, authors opinion about carcinogenicity, and literaturecitation. We refer the reader to the 1984 publications O,S6) for a guide lo tihe plot of thedatabme, a complete description of the numerical index ofcarcinogenic potency, and a d i r w i o n of the sources of data, the rationale for the inclusion of particular experiments and particular target rites, and the conventions adopted in summarizing the literature. The five plotsof the databaseare to be used together, as resullsof individual experiments that were published earlier are not repeated. In all, the five plots include resulls of4487 experiments on lU6 chemicals.


 

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