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Guidelines to Physicians in Conducting Mercury Medical Surveillance Programs

By Environmental Protection Agency

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Book Id: WPLBN0000127212
Format Type: PDF eBook
File Size: 0.1 MB
Reproduction Date: 2007

Title: Guidelines to Physicians in Conducting Mercury Medical Surveillance Programs  
Author: Environmental Protection Agency
Volume:
Language: English
Subject: Ecology, Natural resource issues, Environemtal protection
Collections: Environmental Awareness Library Collection
Historic
Publication Date:
Publisher: United States Environmental Protection Agency

Citation

APA MLA Chicago

Agency, E. P. (n.d.). Guidelines to Physicians in Conducting Mercury Medical Surveillance Programs. Retrieved from http://www.ebooklibrary.org/


Description
Excerpt: Inhalation of mercury vapor is the most important route of uptake for elemental mercury. Approximately 80% of inhaled mercury is retained. Oxidation of elemental mercury (HgE) to divalent mercury (Hg++) is a critical event. Divalent mercury is much less likely to cross cell membranes. The oxidation of elemental mercury to divalent ionic mercury takes place very quickly after absorption, but some elemental mercury remains dissolved in the blood long enough to be carried to and pass through the blood-brain barrier and the placenta. Because of the short transit time from the lung to the brain, the majority of the mercury vapor may arrive at the brain unoxidized.

Table of Contents
Table of Contents 1. INTRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.1 SCOPE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.2 RESPONSIBLE CARE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.3 DEFINITIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 1.4 DISCLAIMER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.5 APPROVAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.6 REVISIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 1.7 REPRODUCTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2. ABSORPTION, DISTRIBUTION, AND EXCRETION . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.1 ABSORPTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.2 DISTRIBUTION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 2.3 ELIMINATION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 3. EXPOSURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3.1 OCCUPATIONAL EXPOSURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 3.2 NON OCCUPATIONAL EXPOSURE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 4. HEALTH EFFECTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 4.1 BIOCHEMICAL INDICATORS OF EFFECT . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 4.2 CLINICAL EFFECTS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 4.3 REPRODUCTION HEALTH CONCERNS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 5. MEDICAL SURVEILLANCE PROGRAM . . . . . . . . . . . . . . . . . . . . . . . . . . 9 5.1 MEDICAL EXAMINATIONS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9 5.2 BIOLOGICAL MONITORING . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10 5.3 MERCURY IN BLOOD . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 13 5.4 WRITTEN OPINION . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 5.5 TEMPORARY REMOVAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14 6. CONTRACTORS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 7. REFERENCES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 8. APPENDIX A - CHECKLIST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 18

 

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