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Pcbs, Pcqs and Pcdfs in Tissues of Yusho and Yu-Cheng Patients

By Miyata, Hideaki

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Book Id: WPLBN0000151368
Format Type: PDF eBook
File Size: 0.4 MB
Reproduction Date: 2005

Title: Pcbs, Pcqs and Pcdfs in Tissues of Yusho and Yu-Cheng Patients  
Author: Miyata, Hideaki
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Miyata, H. (n.d.). Pcbs, Pcqs and Pcdfs in Tissues of Yusho and Yu-Cheng Patients. Retrieved from

Government Reference Publication

Excerpt: In 1968, Yusho occurred in the western part of Japan as a result of ingestion of a rice-bran cooking oil contaminated with a polycholorinated biphenyl (PCB) product. This occurrence affected about 1800 people and was clinically characterized by acnelike dermal lesions and a variety of constitutional symptoms (I) . Many patients have been suffering from it for over 10 years, though the blood levels of PCBs declined rapidly once oil ingestion was terminated and 5 years later were only a few times larger than those of unexposed persons (2). On the other hand, in the cases of workers occupationally exposed to PCBs, only a minority had mild dermal lesions, despite high PCB levels in the blood. Discontinuation of handling PCBs resulted in the rapid disappearance of dermal symptoms in the occupationally exposed group (3,4). Thus, Yusho is clearly symptomatically different from the occupational PCB poisoning. In Japan, however, there has been a tendency to treat cases of the latter or the effect of PCBs as general environmental pollutants as being identical to Yusho. In 1979, another Yusholike disease (Yu-Cheng) occurred in central Taiwan, the Republic of China, with a similar cause as in the case of Yusho (5). About 1700 persons have been suffering from obstinate symptoms as in the Japanese patients.


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