World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Overview of Reproductive and Developmental Toxicity Studies of 1,3-Butadiene in Rodents

By Morrissey, Richard E.

Click here to view

Book Id: WPLBN0000155787
Format Type: PDF eBook
File Size: 0.4 MB
Reproduction Date: 2005

Title: Overview of Reproductive and Developmental Toxicity Studies of 1,3-Butadiene in Rodents  
Author: Morrissey, Richard E.
Volume:
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Historic
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)

Citation

APA MLA Chicago

Morrissey, R. E. (n.d.). Overview of Reproductive and Developmental Toxicity Studies of 1,3-Butadiene in Rodents. Retrieved from http://www.ebooklibrary.org/


Description
Government Reference Publication

Excerpt
Excerpt: Two reports in the literature present information regarding the potential of 1,3-butadiene to cause reproductive or developmental toxicity in laboratory animals. In a reproductive study, male and female rats were exposed to 600,2300, or 6700 ppm of 1,3-butadiene for 8 months (5). A concentration-related depression of body weight was observed. Reproductive studies of male and female animals were performed at unstated times during these exposures, hut no data were given concerning the number of matings or of barren females. The number of litters from female rats in all exposed groups tended to be lower than in controls, although litter sizes were stated to slightly exceed the expected norm of six per litter. Limited breeding tests of the offspring of the 2300- and 6700-ppm exposure groups suggested that there was reduced fecundity, but it was not determined whether the deficit was associated with the males or the females. Although details were not provided, a small number of guinea pigs and rabbits was also used in each exposure group for reproductive studies. Animals of all groups evidently produced progeny, except for rabbits exposed to 600 and 2300 ppm. The basis for the authors conclusion that any apparent reduction in fertility was due to hereditary characteristics is not clear.


 

Click To View

Additional Books


  • Toxicity of Pbbs with Special Reference ... (by )
  • Relative Source Contributions of Diet an... (by )
  • Thyroid Hormone and Brain Development Co... (by )
  • E. Coli Exposed! (by )
  • Renal Ultrastructural and Biochemical In... (by )
  • Niehs/Ntp-Supported Unique Grants Progra... (by )
  • Polychlorinated Biphenyl Exposure and Ef... (by )
  • Essentials of Medical Geology : Impacts ... (by )
  • The Analytical Biochemistry of Chromium (by )
  • Environmental Health Perspectives, Vol. ... (by )
  • Association between Essential Tremor and... (by )
  • Environmental and Toxicological Planning... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World eBook Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.