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Predictiveness and Limitations of Test Methods in Teratology : Overview

By Staples, R. E.

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Book Id: WPLBN0000229929
Format Type: PDF eBook
File Size: 0.1 MB
Reproduction Date: 2005

Title: Predictiveness and Limitations of Test Methods in Teratology : Overview  
Author: Staples, R. E.
Language: English
Subject: Government publications, United Nations., United Nations. Office for Disarmament Affairs
Collections: Government Library Collection, Disarmament Documents
Publication Date:
Publisher: United Nations- Office for Disarmament Affairs (Unoda)


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Staples, R. E. (n.d.). Predictiveness and Limitations of Test Methods in Teratology : Overview. Retrieved from

Government Reference Publication

Excerpt: Compounds intended for marketing by the pharmaceutical industry are tested for possible effects on reproductive processes in much the same way today as was carried out even before November 1961, when the drug thalidomide was related to human malformations. At that time, effects on male and female fertility were sought, but generally only for agents considered likely to alter the endocrinologic status of the patient or that were designed primarily for use by young women. The test species was usually the rat.


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