World Library  


Add to Book Shelf
Flag as Inappropriate
Email this Book

Plos Genetics : Population Structure and Eigenanalysis, Volume 2

By Allison, David B.

Click here to view

Book Id: WPLBN0003923403
Format Type: PDF eBook :
File Size:
Reproduction Date: 2015

Title: Plos Genetics : Population Structure and Eigenanalysis, Volume 2  
Author: Allison, David B.
Volume: Volume 2
Language: English
Subject: Journals, Science, Genetics
Collections: Periodicals: Journal and Magazine Collection (Contemporary), PLoS Genetics
Historic
Publication Date:
Publisher: Plos

Citation

APA MLA Chicago

Allison, D. B. (n.d.). Plos Genetics : Population Structure and Eigenanalysis, Volume 2. Retrieved from http://www.ebooklibrary.org/


Description
Description : Current methods for inferring population structure from genetic data do not provide formal significance tests for population differentiation. We discuss an approach to studying population structure (principal components analysis) that was first applied to genetic data by Cavalli-Sforza and colleagues. We place the method on a solid statistical footing, using results from modern statistics to develop formal significance tests. We also uncover a general ‘‘phase change’’ phenomenon about the ability to detect structure in genetic data, which emerges from the statistical theory we use, and has an important implication for the ability to discover structure in genetic data : for a fixed but large dataset size, divergence between two populations (as measured, for example, by a statistic like FST) below a threshold is essentially undetectable, but a little above threshold, detection will be easy. This means that we can predict the dataset size needed to detect structure.


 

Click To View

Additional Books


  • Plos Genetics : Genetic Interactions of ... (by )
  • Plos Genetics : Nondisjunction of a Sing... (by )
  • Plos Genetics : Incipient Balancing Sele... (by )
  • Plos Genetics : the Mating-type Chromoso... (by )
  • Plos Genetics : Pregnancy-induced Noncod... (by )
  • Plos Genetics : the Genomic Distribution... (by )
  • Plos Genetics : a Wnt-frz, Volume 6 (by )
  • Plos Genetics : Inter-homolog Crossing-o... (by )
  • Plos Genetics : Cdon Mutation and Fetal ... (by )
  • Plos Genetics : a Role for Phosphatidic ... (by )
  • Plos Genetics : Allelic Variation at the... (by )
  • Plos Genetics : Pseudogenization of a Sw... (by )
Scroll Left
Scroll Right

 



Copyright © World Library Foundation. All rights reserved. eBooks from World eBook Library are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.