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Plos One : Variation in Trans-39-hydroxycotinine Glucuronidation Does Not Alter the Nicotine Metabolite Ratio or Nicotine Intake, Volume 8

By Barton, Richard H.

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Book Id: WPLBN0003969350
Format Type: PDF eBook :
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Reproduction Date: 2015

Title: Plos One : Variation in Trans-39-hydroxycotinine Glucuronidation Does Not Alter the Nicotine Metabolite Ratio or Nicotine Intake, Volume 8  
Author: Barton, Richard H.
Volume: Volume 8
Language: English
Subject: Journals, Science, Medical Science
Collections: Periodicals: Journal and Magazine Collection (Contemporary)
Historic
Publication Date:
Publisher: Plos

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Barton, R. H. (n.d.). Plos One : Variation in Trans-39-hydroxycotinine Glucuronidation Does Not Alter the Nicotine Metabolite Ratio or Nicotine Intake, Volume 8. Retrieved from http://www.ebooklibrary.org/


Description
Description : Variation in 3HC glucuronidation activity, including these caused by UGT2B17 gene deletions, did not significantly alter NMR and is therefore unlikely to affect the clinical utility of NMR in smoking behavior and cessation studies. This study demonstrates that NMR is not altered by differences in the rate of 3HC glucuronidation, providing further support that NMR is a reliable indicator of CYP2A6 mediated nicotine metabolism.

 

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